Lenvatinib (Standard), CAS 417716-92-8

Lenvatinib (Standard), CAS 417716-92-8
Artikelnummer
MEXHY-10981R-25
Verpackungseinheit
25 mg
Hersteller
MedChemExpress

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Product Description: Lenvatinib (Standard) is the analytical standard of Lenvatinib. This product is intended for research and analytical applications. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2].

Formula: C21H19ClN4O4

References: [1]Kudo M, et al. Lenvatinib versus Bay 43-9006 in first-line treatment of patients with unresectable hepatocellularcarcinoma: a randomised phase 3 non-inferiority trial. Lancet. 2018 Mar 24;391(10126):1163-1173./[2]Suyama K, et al. Lenvatinib: A Promising Molecular Targeted Agent for Multiple Cancers. Cancer Control. 2018 Jan-Dec;25(1):1073274818789361./[3]Matsui J, et al. E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008, 122(3), 664-671./[4]Matsui J, et al. Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase. Clin Cancer Res. 2008, 14(17),545.

CAS Number: 417716-92-8

Molecular Weight: 426.85

Compound Purity: 99.77

Research Area: Cancer

Target: c-Kit;FGFR;PDGFR;Reference Standards;RET;VEGFR
Mehr Informationen
Artikelnummer MEXHY-10981R-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-10981R-25
Verpackungseinheit 25 mg
Mengeneinheit STK
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