Product Description: LEQ803 (N-Desmethyl Ribociclib) is a drug metabolite of the CDK4/6 inhibitor Ribociclib (HY-15777), which is produced through metabolism by CYP3A4. LEQ803 has potential application value in the field of oncology[1].
Formula: C22H28N8O
References: [1]James AD, et al. An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data. Pharmacol Res Perspect. 2020 Jun;8(3):e00599.
CAS Number: 1211441-59-6
Molecular Weight: 420.51
Research Area: Cancer
Target: Cytochrome P450;Drug Metabolite