Product Description: Lynestrenol (Standard) is the analytical standard of Lynestrenol. This product is intended for research and analytical applications. Lynestrenol is a pregnane X receptor (PXR) agonist with the EC50s of 41 and 0.23 μM for hPXR and zfPXR, respectively[1]. Lynestrenol, a synthetic progesteronelike agent possess immunostimulatory properties[2][3].
Formula: C20H28O
References: [1]Nicolas Creusot, et al. A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays. Front Endocrinol (Lausanne). 2021 May 18;12:665521./[2]J Wybran. Lynestrenol: a progesteronelike agent with immunostimulatory properties. Recent Results Cancer Res. 1980;75:180-4./[3]Yasir Hasan Siddique, et al. In vivo induction of sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) by lynestrenol. Indian J Exp Biol. 2005 Mar;43(3):291-3.
CAS Number: 52-76-6
Molecular Weight: 284.44
Research Area: Endocrinology; Inflammation/Immunology
Target: Orphan Receptor;Reference Standards
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