Product Description: MAO-B-IN-43 (4) is a potent hMAO-B inhibitor and a weak GSK3β kinase inhibitor, with Ki values of 0.044 μM and 0.004 μM for hMAO-A and hMAO-B, respectively. MAO-B-IN-43 (4) can be used for the research of neurodegenerative disorder[1].
Formula: C14H11Cl2N3O
References: [1]Maria Luisa Di Paolo, et al. 2-(Phenylamino)-7,8-dihydroquinazolin-5(6H)-one, a promising scaffold for MAO-B inhibitors with potential GSK3β targeting. Eur J Med Chem. 2025 Jul 5:291:117580.
Molecular Weight: 308.16
Research Area: Neurological Disease
Target: GSK-3;Monoamine Oxidase