MDI-114215

Product Description: MDI-114215 (compound 85) is an allosteric LIMK1/2 dual inhibitor with good in vivo tolerance. MDI-114215 can inhibit cofilin phosphorylation in mouse brain region-induced pluripotent stem cells (iPSCs), which can be used for Fragile X Syndrome (FXS) research[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C26H29N3O4S

References: [1]Baldwin AG, et al. Discovery of MDI-114215: A Potent and Selective LIMK Inhibitor To Treat Fragile X Syndrome. J Med Chem. 2025 Jan 9;68(1):719-752.

Molecular Weight: 479.59

Research Area: Metabolic Disease

Target: LIM Kinase (LIMK)

• Artikelnummer: MEXHY-170781-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170781-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK