Product Description: MurA-IN-5 (compound 4c) exhibits (MIC) = 1.95 μg/mL against Escherichia coli and demonstrating significant potency as a MurA inhibitor with (IC50) of 3.77 μg/mL. MurA-IN-5 displays an antibiofilm activity against multiple microorganisms, indicating its potential to combat biofilm-related infections[1].
Formula: C33H28N6O2
References: [1]Omkulthom Al Kamaly, et al. Insights into Novel Arylazopyrazolo[1,5-a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking. ACS Omega. 2025 Jan 24;10(4):4044-4056.
Molecular Weight: 540.61
Research Area: Infection
Target: Bacterial