Netupitant (Standard), CAS 290297-26-6

Netupitant (Standard), CAS 290297-26-6
Artikelnummer
MEXHY-16346R-25
Verpackungseinheit
25 mg
Hersteller
MedChemExpress

Verfügbarkeit: wird geladen...
Preis wird geladen...
Product Description: Netupitant (Standard) is the analytical standard of Netupitant. This product is intended for research and analytical applications. Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK1) receptor antagonist with a Ki of 0.95 nM for hNK1 in CHO cells. Netupitant has antiemetic affect[1][2][3].

Formula: C30H32F6N4O

References: [1]Hoffmann T, et al. Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1362-5./[2]Rizzi A, et al. In vitro and in vivo pharmacological characterization of the novel NK1 receptor selective antagonist Netupitant. Peptides. 2012 Sep;37(1):86-97./[3]Stefano Palea, et al. Netupitant, a Potent and Highly Selective NK1 Receptor Antagonist, Alleviates Acetic Acid-Induced Bladder Overactivity in Anesthetized Guinea-Pigs. Front Pharmacol. 2016 Aug 4;7:234.

CAS Number: 290297-26-6

Molecular Weight: 578.59

Research Area: Neurological Disease; Endocrinology

Target: Neurokinin Receptor;Reference Standards
Mehr Informationen
Artikelnummer MEXHY-16346R-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-16346R-25
Verpackungseinheit 25 mg
Mengeneinheit STK
Produktinformation (PDF)
×
MSDS (PDF)
×