NLRP3-IN-69, CAS 3027608-60-9

Product Description: NLRP3-IN-69 (Compound 23) inhibits the activation of NF-κB p65 and the formation of NLRP3 inflammasome. NLRP3-IN-69 inhibits LPS (HY-D1056)-induced overexpression of IL-1β, iNOS and COX-2, inhibits NO generation (IC50=5.66 μM), thereby exhibiting anti-inflammatory activity[1].

Formula: C25H24O7

References: [1]Yu J, et al., Novel Cinnamic Acid Derivatives Containing Naproxen as NLRP3 Inhibitors: Synthesis and Evaluation of Their Biological Activity. Chem Biodivers. 2024 Dec 29:e202402700.

CAS Number: 3027608-60-9

Molecular Weight: 436.45

Research Area: Inflammation/Immunology

Target: COX;Interleukin Related;NF-κB;NO Synthase;NOD-like Receptor (NLR)

• Artikelnummer: MEXHY-170836-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170836-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK