NQO2-IN-1, CAS 2920687-14-3

Product Description: NQO2-IN-1 (Compound 20b) is the inhibitor for quinone oxidoreductase (NQO) that inhibits NQO2 with an IC50 of 95 nM. NQO2-IN-1 overcomes the resistance of NSCLC cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by induction of ROS and apoptosis[1].

Formula: C18H18N2O3

References: [1]Qi SJ, et al., Discovery of potent quinone oxidoreductase 2 inhibitors to overcome TRAIL resistance of non-small cell lung cancer. Eur J Med Chem. 2025 Feb 16;288:117382.

CAS Number: 2920687-14-3

Molecular Weight: 310.35

Research Area: Cancer

Target: Apoptosis;Reactive Oxygen Species

• Artikelnummer: MEXHY-168926-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-168926-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK