Olprinone, CAS 106730-54-5

Olprinone, CAS 106730-54-5
Artikelnummer
MEXHY-14254A-25
Verpackungseinheit
25 mg
Hersteller
MedChemExpress

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Product Description: Olprinone (Loprinone) is a potent phosphodiesterase (PDE) 3 inhibitor, with IC50s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C14H10N4O

References: [1]Sugioka M, et al. Identification and characterization of isoenzymes of cyclic nucleotide phosphodiesterase in human kidney and heart, and the effects of new cardiotonic agents on these isoenzymes. Naunyn Schmiedebergs Arch Pharmacol. 1994;350(3):284-293./[2]Di Paola R, et al. Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats. Eur J Pharmacol. 2011;650(2-3):612-620.

CAS Number: 106730-54-5

Molecular Weight: 250.26

Compound Purity: 99.29

Research Area: Cardiovascular Disease

Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Phosphodiesterase (PDE)
Mehr Informationen
Artikelnummer MEXHY-14254A-25
Hersteller MedChemExpress
Hersteller Artikelnummer HY-14254A-25
Verpackungseinheit 25 mg
Mengeneinheit STK
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