PARP1-IN-34

Product Description: PARP1-IN-34 (compound 30) is a selective PARP1 inhibitor with an IC50 of 0.32 nM. PARP1-IN-34 is a subnanomolar PARP1 inhibitor with >1000-fold selectivity against PARP2 with an IC50 of 326 nM. PARP1-IN-34 shows antitumor efficacy[1].

Applications: Cancer-programmed cell death

Formula: C23H27N7O2

References: [1]Gao S, Hou Y, et al. Discovery of Pyrazolo[1,5,4-de]quinoxalin-2(3H)-one Derivatives as Highly Potent and Selective PARP1 Inhibitors. J Med Chem. 2024 Dec 12;67(23):21380-21399.

Molecular Weight: 433.51

Research Area: Cancer

Target: PARP

• Artikelnummer: MEXHY-170432-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-170432-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK