Product Description: Promestriene is a synthetic diethyl-ether of estradiol and a locally effective estrogen. Promestriene has an efficient action on vaginal atrophy while it is minimally absorbed[1][2].
Applications: Cancer-programmed cell death
Formula: C22H32O2
References: [1]Isabel Santos, et al. Urogenital Disorders Associated With Oestrogen Deficiency: The Role of Promestriene as Topical Oestrogen Therapy. Gynecol Endocrinol. 2010 Sep;26(9):644-51./[2]Lino Del Pup, et al. Promestriene, a Specific Topic Estrogen. Review of 40 Years of Vaginal Atrophy Treatment: Is It Safe Even in Cancer Patients. Anticancer Drugs. 2013 Nov;24(10):989-98./[3]AJO Almodovar, et al. Abstract P5-05-07: Promestriene effects on estrogen-sensitive breast cancer cell proliferation in vitro. Cancer Res 2013;73(24 Suppl): Abstract nr P5-05-07.
CAS Number: 39219-28-8
Molecular Weight: 328.49
Compound Purity: 99.91
Research Area: Cancer; Endocrinology
Solubility: DMSO : 20 mg/mL (ultrasonic)
Target: Estrogen Receptor/ERR
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