PROTAC WDR5 degrader 1, CAS 2737222-94-3

Product Description: PROTAC WDR5 degrader 1 (compound 8g) is a PROTAC degrader targeting WDR5. PROTAC WDR5 degrader 1 is composed of a target protein ligand (red part) WDR5 ligand 2 (HY-168488), a VHL-type E3 ligase ligand (blue part) (S,R,S)-AHPC (HY-125845), and a PROTAC linker (balck part) 5-Aminovaleric acid (HY-W015878), in which the VHL ligand and the PROTAC linker form a conjugate (HY-114176A)[1].

Applications: Cancer-programmed cell death

Formula: C52H60F3N9O7S

References: [1]Dölle A, et al. Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. J Med Chem. 2021 Aug 12;64(15):10682-10710.

CAS Number: 2737222-94-3

Molecular Weight: 1012.15

Research Area: Others

Target: DNA/RNA Synthesis;PROTACs;WDR5

• Artikelnummer: MEXHY-168487-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-168487-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK