(S)-CE-123, CAS 2378384-49-5

(S)-CE-123, CAS 2378384-49-5
Artikelnummer
MEXHY-163384-5
Verpackungseinheit
5 mg
Hersteller
MedChemExpress

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Product Description: (S)-CE-123 is a potent, selective, and novel atypical dopamine transporter (DAT) inhibitor with an EC50 of 2.76 μM in uptake inhibition assays conducted in HEK293 cells stably expressing human isoforms of DAT. (S)-CE-123, a Modafinil analogue, is able to penetrate the blood–brain barrier. (S)-CE-123 improves cognitive and motivational processes in experimental animals[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C17H15NOS2

References: [1]Renee A Rotolo, et al. The Novel Atypical Dopamine Uptake Inhibitor (S)-CE-123 Partially Reverses the Effort-Related Effects of the Dopamine Depleting Agent Tetrabenazine and Increases Progressive Ratio Responding. Front Pharmacol. 2019 Jun 28:10:682. /[2]Eduardo R. Perez Gonzalez, et al. Process Development and Scale-Up of a Novel Atypical DAT Inhibitor (S)-CE-123. ACS Omega 2024, March 4.

CAS Number: 2378384-49-5

Molecular Weight: 313.44

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Dopamine Transporter
Mehr Informationen
Artikelnummer MEXHY-163384-5
Hersteller MedChemExpress
Hersteller Artikelnummer HY-163384-5
Verpackungseinheit 5 mg
Mengeneinheit STK
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