Product Description: (S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design PROTACs[1].
Applications: Cancer-programmed cell death
Formula: C31H44N4O6S
References: [1]Sun N, et al. Discovery of the First Lactate Dehydrogenase Proteolysis Targeting Chimera Degrader for the Treatment of Pancreatic Cancer. J Med Chem. 2023 Jan 12;66(1):596-610.
CAS Number: 2172819-76-8
Molecular Weight: 600.77
Compound Purity: 98.71
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: E3 Ligase Ligand-Linker Conjugates