Product Description: (S,R,S)-AHPC-C3-COOH (compound 28i) is a carboxylic acid derivative of the VHL E3 ubiquitin ligase ligand-Linker conjugate. (S,R,S)-AHPC-C3-COOH can be used to synthesize PROTACs[1].
Applications: Cancer-programmed cell death
Formula: C27H36N4O6S
References: [1]Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298.
CAS Number: 2172819-73-5
Molecular Weight: 544.66
Research Area: cancer
Solubility: 10 mM in DMSO
Target: E3 Ligase Ligand-Linker Conjugates