SMW139, CAS 2133010-38-3

SMW139, CAS 2133010-38-3
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MEXHY-171462-0
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MedChemExpress

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Product Description: SMW139 is a selective allosteric antagonist of P2X7 receptor, with a Ki value of 32 nM for human P2X7R. The half-life of SMW139 in rat liver microsomes is 47 minutes. SMW139 can be used for inflammation, Alzheimer’s disease, multiple sclerosis study[1].

Formula: C19H21ClF3NO2

References: [1]Janssen B, et al. Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation. Sci Rep. 2018 Apr 26;8(1):6580.

CAS Number: 2133010-38-3

Molecular Weight: 387.82

Research Area: Inflammation/Immunology; Neurological Disease

Target: Interleukin Related;P2X Receptor
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Artikelnummer MEXHY-171462-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-171462-0
Verpackungseinheit Get quote
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