Product Description: SP4e is an activator of PPAR-γ, with the EC50 of 739 nM in HK-2 cells. SP4e reduces the blood glucose levels and lipid peroxidation, and increases glutathione levels and catalase activityin the Swiss albino mice[1].
Applications: Metabolism-sugar/lipid metabolism
Formula: C22H17ClN2O2S2
References: [1]Gupta S, et al. Integrated fragment-based drug design and virtual screening techniques for exploring the antidiabetic potential of thiazolidine-2,4-diones: Design, synthesis and in vivo studies [published online ahead of print, 2023 Sep 21]. Eur J Med Chem. 2023;261:115826.
Molecular Weight: 440.97
Compound Purity: 99.72
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: PPAR