Suplatast (Tosilate), CAS 94055-76-2

Suplatast (Tosilate), CAS 94055-76-2
Artikelnummer
MEXHY-17002-1G
Verpackungseinheit
1 g
Hersteller
MedChemExpress

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Product Description: Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity[1][2][3][4].

Applications: COVID-19-immunoregulation

Formula: C23H33NO7S2

References: [1]Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N. Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice. J Pharmacol Exp Ther. 2009 Jan;328(1):55-61./[2]Yanagihara Y, et, al. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2). Regulation of human IgE response. Jpn J Pharmacol. 1993 Jan;61(1):31-9./[3]Zhao GD, et, al. Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness. Int Arch Allergy Immunol. 2000 Feb;121(2):116-22./[4]Kurokawa M, et, al. Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 2001 Dec;10(6):333-7.

CAS Number: 94055-76-2

Molecular Weight: 499.64

Compound Purity: 99.67

Research Area: Inflammation/Immunology

Solubility: DMSO : ≥ 33 mg/mL/H2O : ≥ 100 mg/mL

Target: Interleukin Related
Mehr Informationen
Artikelnummer MEXHY-17002-1G
Hersteller MedChemExpress
Hersteller Artikelnummer HY-17002-1G
Verpackungseinheit 1 g
Mengeneinheit STK
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