TBK1-IN-2, CAS 3075572-35-6

Product Description: TBK1-IN-2 (Compound A1) is a potent TBK1 inhibitor (IC50: 775 pM). TBK1-IN-2 binds to TBK1 through stable hydrogen bonds and π-π stacking, inhibiting IRF3 phosphorylation. TBK1-IN-2 synergizes with TNF/IFNγ to enhance immune-mediated tumor cell death. TBK1-IN-2 can be used in cancer immunotherapy research[1].

Formula: C26H29N7O5

References: [1]Sun W, et al. Structure-Based Optimization of TBK1 Inhibitors. ACS Med Chem Lett. 2025 Mar 31;16(4):611-616.

CAS Number: 3075572-35-6

Molecular Weight: 519.55

Research Area: Cancer

Target: IKK

• Artikelnummer: MEXHY-173462-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-173462-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK