TEAD-IN-8, CAS 1008768-41-9

Product Description: TEAD-IN-8 is a novel TEAD inhibitor, which potently and specifically inhibits TEAD-YAP transcriptional activities. TM2, alone or in combination with MEK inhibitors, exhibits potent antiproliferative effects in YAP-dependent cancer cells[1].

Applications: Cancer-programmed cell death

Formula: C26H33N3O3

References: [1]Hu L, et al. Discovery of a new class of reversible TEA domain transcription factor inhibitors with a novel binding mode. Elife. 2022 Nov 18;11:e80210.

CAS Number: 1008768-41-9

Molecular Weight: 435.56

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: YAP

• Artikelnummer: MEXHY-163173-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-163173-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK