Thalidomide-O-amide-C5-NH2 (TFA), CAS 2748161-83-1

Product Description: Thalidomide-O-amide-C5-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

Applications: Cancer-programmed cell death

Formula: C22H25F3N4O8

References: [1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11./[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

CAS Number: 2748161-83-1

Molecular Weight: 530.45

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;E3 Ligase Ligand-Linker Conjugates

• Artikelnummer: MEXHY-141423A-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-141423A-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK