Product Description: TRIM24/BRPF1-IN-2 (compound 20l) is a potent TRIM24/BRPF1 dual inhibitor, with IC50 values of 0.98 and 1.16 μM, respectively. TRIM24/BRPF1-IN-2 shows TRIM24/BRPF1 bromodomain binding affinity. TRIM24/BRPF1-IN-2 can be used for prostate cancer research[1].
Applications: Cancer-programmed cell death
Formula: C20H22N2O4S
References: [1]Xiang Q, et al. Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors. Eur J Med Chem. 2022 Jun 5;236:114311.
CAS Number: 3033288-68-2
Molecular Weight: 386.46
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Epigenetic Reader Domain