TrxR1-IN-2

Product Description: TrxR1-IN-2 (Compound 6a) is a TrxR1 inhibitor that covalently binds to the Cys475 and Sec498 sites of TrxR1, thereby inhibiting TrxR1 activity and leading to redox homeostasis disruption, which triggers apoptosis and ferroptosis[1].

Formula: C19H23NO6

References: [1]Ren H, et al. Design of ROS-Triggered Sesquiterpene Lactone SC Prodrugs as TrxR1 Covalent Inhibitors for the Treatment of Non-Small Cell Lung Cancer[J]. Journal of Medicinal Chemistry, 2025.

Molecular Weight: 361.39

Research Area: Cancer

Target: Apoptosis;Ferroptosis;TrxR

• Artikelnummer: MEXHY-168874-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-168874-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK