WB436B, CAS 2248552-84-1

Product Description: WB436B is a highly selective STAT3 inhibitor. WB436B can selectively inhibit STAT3-Tyr705 phosphorylation and the expression of STAT3 target genes, showing cytotoxic effects on pancreatic cancer cells and inducing apoptosis. WB436B can suppress tumor growth and metastasis in pancreatic cancer mouse models, extending the survival of tumor-bearing mice[1].

Formula: C21H20N6O3S

References: [1]Chen H, et al. Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer. Clin Cancer Res. 2023 Feb 16;29(4):815-830.

CAS Number: 2248552-84-1

Molecular Weight: 436.49

Compound Purity: 99.93

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Apoptosis;STAT

• Artikelnummer: MEXHY-164546-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-164546-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK