Product Description: WR-27653 (RC-12) is a derivative of Catechol with good activity against hypnozoites in the gold-standard Plasmodium cynomolgi-rhesus monkey (Macaca mulatta) model. WR-27653 has antimalarial activity[1][2].
Formula: C20H36BrN3O2
References: [1]Werbel LM, et al. Synthesis and physical properties of the antimalarial agent 4-(2-bromo-4,5-dimethoxyphenyl)-1,1,7,7-tetraethyldiethylenetriamine (RC-12) (WR-27,653). J Pharm Sci. 1967 Oct;56(10):1335-7. /[2]Dong Y, et al. Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12). ACS Omega. 2022 Mar 30;7(14):12401-12411.
CAS Number: 6042-36-0
Molecular Weight: 430.42
Research Area: Infection
Target: Drug Derivative;Parasite