ZL0516, CAS 2230496-93-0

Product Description: ZL0516 is a potent, selective, and orally active BRD4 BD1 inhibitor. ZL0516 suppresses inflammatory bowel disease (IBD) by inhibiting BRD4/NF-κB signaling[1].

Formula: C27H34N2O6

References: [1]Ma Z, et al. Orally Bioavailable BRD4 BD1 Inhibitor ZL0516 Effectively Suppresses Colonic Inflammation in Animal Models of Inflammatory Bowel Disease. ACS Pharmacol Transl Sci. 2025 Apr 1;8(4):1152-1167./[2]Lu J, et al. Rational Design of the First Dual Agonist at Trace Amine-Associated Receptor 1 and 5-HT2C Receptors Based on Binding Pocket Similarity for the Treatment of Schizophrenia and Alzheimer's Disease-Related Psychosis. J Med Chem. 2025 Apr 10;68(7):7082-7105.

CAS Number: 2230496-93-0

Molecular Weight: 482.57

Research Area: Inflammation/Immunology

Target: Epigenetic Reader Domain

• Artikelnummer: MEXHY-173450-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-173450-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK