Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 8-(3,6-dihydro-2H-pyran-4-yl)-2-phenyl-6-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-imidazo[1,2-a]pyrazine
Purity: ≥98%
Formula Markup: C25H26N6O
Formula Weight: 426.51378
CAS Number: 3023925-68-7
Notes: A ferroptosis inhibitor; inhibits erastin-induced increases in ferrous iron levels and ferroptosis in ES-2 cells at 0.3 µM; increases NCOA4 and ferritin levels in ES-2 cells at 10 µM; decreases serum Alt and Ast levels, reduces liver and serum MDA levels, and increases liver ferritin levels in a mouse model of acetaminophen-induced acute liver injury at 3 mg/kg