YM-1 (trifluoroacetate salt)

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2-((3-ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-1-methylpyridin-1-ium, monotrifluoroacetate salt

Purity: ≥98%

Formula Markup: C20H20N3OS2 / CF3COO

Formula Weight: 495.535209

Notes: An allosteric Hsp70 modulator; binds to the Hsp70 N-terminal NBD and inhibits ATP/ADP turnover thereby promoting substrate binding to the C-terminal SBD; reduces the viability of MCF-7 breast cancer cells at 3 and 10 µM; induces BRD4 degradation in MCF-7 cells; lowers mHTTQ74 levels and decreases the proportion of mHTTQ74 aggregates found in the nucleus over the cytoplasm in PC12 cells at 3 µM

• Artikelnummer: CAY41174-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41174-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK