Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 10-[2-[bis(2-hydroxydecyl)amino]ethyl]-15-hydroxy-7,13-bis(2-hydroxydecyl)-N,N-dimethyl-4-oxo-N-(3-sulfopropyl)-3,7,10,13-tetraazatricosan-1-aminium, inner salt
Purity: ≥95%
Formula Markup: C66H138N6O9S
Formula Weight: 1191.90296
CAS Number: 2090299-48-0
Notes: A zwitterionic aminolipid; has been used in the generation of LNPs for the delivery of mRNA and sgRNA in vitro and in vivo; LNPs containing ZA3-Ep10 selectively accumulate in the liver, lung, and kidneys over the heart and spleen in mice; ZA3-Ep10-containing LNPs encapsulating sgRNA targeting DNA encoding luciferase eliminate luciferase activity in HeLa-Luc-Cas9 cells