CD40L ELISA Kit (Human)

Description of Target: Cytokine that binds to CD40/TNFRSF5 (PubMed:1280226). Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (PubMed:8617933). Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Induces tyrosine phosphorylation of isoform 3 of CD28 (PubMed:15067037). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (By similarity).

Protein Name: CD40 ligand

Sample Type: serum, plasma, tissue homogenates, cell lysates or other biological fluids.

Sensitivity: 0.051ng/mL

Specificity#: This assay has high sensitivity and excellent specificity for detection of CD40L.
No significant cross-reactivity or interference between CD40L and analogues was observed.

• Artikelnummer: AVIOKDD01926-96
• Hersteller: Aviva Systems Biology
• Hersteller Artikelnummer: OKDD01926-96W
• Verpackungseinheit: 96 Wells
• Mengeneinheit: PAK
• Reaktivität: Human
• Methode: Enzyme-linked Immunosorbent Assay
• Human Gene ID: 959