Target Synonym: FOS;AP-1;C-FOS;p55;c-Fos
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Immunogen: A synthetic peptide of human FOS
Dilution: WB 1:500-1:2000
Calculated MW: 28kDa/36kDa/40kDa
Observed MW: 62KDa