FTI-277 (hydrochloride), CAS 261636-47-9

Shelf life (days): 1460

Info: An FTase inhibitor (IC50 = 0.1 µM); selective for FTase over GGTase (IC50 = >10 µM); inhibits IL-1β-induced production of NO in primary rat pulmonary artery smooth muscle cells at 10 µM; decreases the proliferation of A549 cells when used at 10 µM and induces cell cycle arrest at the G2/M phase in the same cells at 20 µM; increases the diameter of basilar arteries, improves appetite, and increases activity in a dog model of subarachnoid hemorrhage-induced vasospasm when intracisternally administered

Formulation: A solid

Formal Name: N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine, methyl ester, hydrochloride

Purity: ≥98%

Formula Markup: C22H29N3O3S2 • XHCl

Formula Weight: 447.612

CAS Number: 261636-47-9

• Artikelnummer: CAY10011667-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10011667-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK