Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: O-2-amino-2,7-dideoxy-D-glycero-a-D-gluco-heptopyranosyl-(1?4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-ß-L-arabinopyranosyl-(1?6)]-2-deoxy-D-streptamine, disulfate
Purity: ≥95%
Formula Markup: C20H40N4O10 / 2H2SO4
Formula Weight: 692.7
CAS Number: 108321-42-2
Notes: G-418 is an aminoglycoside antibiotic.{22696} It is active against T. thermophila (IC50 = 10 µM). It inhibits the 80S ribosome and protein elongation during translation in a cell-free assay when used at a concentration of 2 nM.{66212} G-418 is used in molecular biology as a selective agent in cell lines or plasmids containing the neomycin resistance gene, neoR.{66211} It increases survival in mouse models of Salmonella, P. vulgaris, K. pneumoniae, or E. coli when administered at doses ranging from 0.8 to 4 mg/kg.{66213}
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