Shelf life (days): 730.0
Formulation: A solution in ethanol
Formal Name: 6Z,9Z,12Z-octadecatrienoic acid, ethyl ester
Purity: ≥98%
Formula Markup: C20H34O2
Formula Weight: 306.5
CAS Number: 31450-14-3
Notes: γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak leukotriene B4 (LTB4) receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki value of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361} GLA ethyl ester is an esterified version of the free acid which is less water soluble but more amenable for the formulation of GLA-containing diets.