GABA A Receptor Alpha-1 Antibody, Clone N95/35: RPE

Mouse Anti-Human GABA-A Receptor Alpha-1 Monoclonal IgG2A

Target: GABA A Receptor

Conjugate: RPE

Product Type: Monoclonal

Clone Number: N95/35 (Formerly sold as S95-35)

Immunogen: Fusion protein amino acids 355-394 of human GABA-A-R-Alpha1

Swiss-Prot: P14867

Purification: Protein G Purified

Storage Buffer: 95.64mM Phosphate, 2.48mM MES and 2mM EDTA

Concentration: 1 mg/ml

Specificity: Detects ~55kDa. No cross-reactivity against GABA-A-R-Alpha 2 or –Alpha3.

Cellular Localization: Cell Membrane / Cell Junction / Synapse / Postsynaptic Cell Membrane

Scientific Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (1). GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain (2).

References: 1. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136.2. Macdonald R.L., Olsen R.W. (1993) Annu Rev Neurosci. 17: 569-602.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-346D-RPE
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-346D-RPE
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2a
• Human Gene ID: 14394
• Wirt: Mouse
• Konjugat: Conjugated, R-Phycoerythrin