Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: (7ß,15a,20E)-7,15-dihydroxy-3,11,23-trioxo-lanosta-8,20(22)-dien-26-oic acid
Purity: ≥95%
Formula Markup: C30H42O7
Formula Weight: 514.65028
CAS Number: 100665-40-5
Notes: Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities.{48894,48895,48896} It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes).{48895} Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 µg/ml.{48896}