Product Description: Gemcitabine elaidate (CP-4126) is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate exhibits anti-tumor activity[1][2].
Applications: Cancer-Kinase/protease
Formula: C27H43F2N3O5
References: [1]Bergman AM, et, al. Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models. Invest New Drugs. 2011 Jun;29(3):456-66./[2]Adema AD, et, al. Cell cycle effects of fatty acid derivatives of cytarabine, CP-4055, and of gemcitabine, CP-4126, as basis for the interaction with oxaliplatin and docetaxel. Int J Oncol. 2010 Jan;36(1):285-94.
CAS Number: 210829-30-4
Molecular Weight: 527.64
Compound Purity: 99.14
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: Apoptosis;Autophagy;Nucleoside Antimetabolite/Analog
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