Conjugation: HRP: Horseradish Peroxidase
Description of Target: Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).
Immunogen: The immunogen is a synthetic peptide directed towards the following sequence LENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGT
Molecular Weight: 113 kDa
Peptide Sequence: Synthetic peptide located within the following region:
LENSGWITQYTPYQPEVSQGRLESLLNYQTMVCDITGLDMANASLLDEGTProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Glycine dehydrogenase [decarboxylating], mitochondrial
Protein Size: 1020
Purification: Affinity Purified
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