GLX-351322, CAS 835598-94-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid, ethyl ester

Purity: ≥98%

Formula Markup: C21H25N3O5S

Formula Weight: 431.50642

CAS Number: 835598-94-2

Notes: GLX-351322 is an inhibitor of NADPH oxidase 4 (NOX4; IC50 = 5 µM).{61052} It is selective for NOX4 over NOX2 (IC50 = 40 µM). GLX-351322 (10 µM) reduces glucose-induced production of reactive oxygen species (ROS) and cytotoxicity in isolated human pancreatic islets. It decreases blood glucose levels in an intravenous glucose tolerance test in mice fed a high-fat diet when administered in the drinking water at an estimated dose of 3.8 mg/kg per day.

• Artikelnummer: CAY31523-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31523-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK