GNE-049, CAS 1936421-41-8

Product Description: GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively[1].

Applications: Cancer-programmed cell death

Formula: C27H32F2N6O2

References: [1]Romero FA, et al. GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). J Med Chem. 2017 Nov 22;60(22):9162-9183.

CAS Number: 1936421-41-8

Molecular Weight: 510.58

Compound Purity: 99.33

Research Area: Cancer

Target: Epigenetic Reader Domain;Histone Acetyltransferase

• Artikelnummer: MEXHY-108435-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-108435-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK