GPX4-IN-5, CAS 2922824-09-5

Product Description: GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].

Applications: Cancer-programmed cell death

Formula: C18H17ClFNO5

References: [1]Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

CAS Number: 2922824-09-5

Molecular Weight: 381.78

Compound Purity: 99.90

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Ferroptosis;Glutathione Peroxidase

• Artikelnummer: MEXHY-155663-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-155663-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK