GSK-3β inhibitor 1, CAS 187325-53-7

Product Description: GSK-3β inhibitor 1 (compound 3a) inhibits GSK-3β with an IC50 of 4.19 nM. GSK-3β inhibitor 1 demonstrates high antidiabetic efficacy in obese Streptozotocin (HY-13753)-treated rats[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C14H10N2O

References: [1]Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.

CAS Number: 187325-53-7

Molecular Weight: 222.25

Compound Purity: 98.04

Research Area: Cancer; Metabolic Disease

Solubility: DMSO : 33.33 mg/mL (ultrasonic)

Target: GSK-3

• Artikelnummer: MEXHY-126144-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-126144-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK