GSK620, CAS 2088410-46-0

Product Description: GSK620 is a potent and orally active pan-BD2 inhibitor with excellent broad selectivity, developability and in vivo oral pharmacokinetics. GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood[1].

Applications: COVID-19-immunoregulation

Formula: C18H19N3O3

References: [1]Seal JT, et al. The Optimization of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor. J Med Chem. 2020;63(17):9093-9126.

CAS Number: 2088410-46-0

Molecular Weight: 325.36

Compound Purity: 99.79

Research Area: Inflammation/Immunology

Solubility: DMSO : 35 mg/mL (ultrasonic)

Target: Epigenetic Reader Domain

• Artikelnummer: MEXHY-137892-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-137892-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK