Conjugation: HRP: Horseradish Peroxidase
Description of Target: GSR belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. It maintains high levels of reduced glutathione in the cytosol. Both glutathione and glutathione reductase are inducible by D3T, and that upregulation of GSH biosynthesis underlies D3T-mediated cytoprotection against ROS/RNS-elicited injury to human vascular smooth muscle cells.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GSR
Key Reference: Senturk,M., (2008) J Enzyme Inhib Med Chem 23 (1), 144-148
Molecular Weight: 56kDa
Peptide Sequence: Synthetic peptide located within the following region:
PTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Glutathione reductase, mitochondrial
Protein Size: 522
Purification: Affinity Purified
Deutsch
English
