Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid, dihydrochloride
Purity: ≥90% (mixture of isomers)
Formula Markup: C34H38N4O6 / 2HCl
Formula Weight: 671.61016
CAS Number: 17696-69-4
Notes: Hematoporphyrin is a photosensitizer.{46544} Hematoporphyrin (3 μM) increases oxygen consumption and decreases the respiratory control ratio (RCR) in irradiated isolated rat liver mitochondria.{46545} It induces DNA breaks in cell-free assays, but not in human HeLa cervical cancer cells, in a light-dependent manner when used at a concentration of 6 μM.{46546} Hematoporphyrin (12 μM) decreases the survival of irradiated, but not non-irradiated, HeLa cells. Hematoporphyrin (5 mg/kg) decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation.{46547}
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