Product Description: Hesperetin 7-O-glucoside is a typical flavonoid monoglucoside, which is an anti-inflammatory agent and an antihypertensive with orally active. Hesperetin 7-O-glucoside is a commonly used food adjuvant. Hesperetin 7-O-glucoside inhibits human intestinal maltase and human HMG-CoA reductase with Ki of 1.8 mM and 9.8 μM, respectively. Hesperetin 7-O-glucoside has antibacterial activity and can regulate intestinal flora and metabolic homeostasis in mice[1][2][3].
Applications: Metabolism-sugar/lipid metabolism
Formula: C22H24O11
References: [1]Young-Su Lee, et al. Enzymatic Bioconversion of Citrus Hesperidin by Aspergillus Sojae Naringinase: Enhanced Solubility of hesperetin-7-O-glucoside With in Vitro Inhibition of Human Intestinal Maltase, HMG-CoA Reductase, and Growth of Helicobacter Pylori. Food Chem. 2012 Dec 15;135(4):2253-9./[2]Wu F, et al. In Vitro and In Vivo Studies Reveal that Hesperetin-7-O-glucoside, a Naturally Occurring Monoglucoside, Exhibits Strong Anti-inflammatory Capacity. J Agric Food Chem. 2021 Nov 3;69(43):12753-12762./[3]Wu F, et al. Short-Term Intake of Hesperetin-7-O-Glucoside Affects Fecal Microbiota and Host Metabolic Homeostasis in Mice. J Agric Food Chem. 2021 Feb 10;69(5):1478-1486.
CAS Number: 31712-49-9
Molecular Weight: 464.42
Compound Purity: 98.08
Research Area: Infection; Metabolic Disease; Inflammation/Immunology
Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 80°C)
Target: Bacterial;HMG-CoA Reductase (HMGCR);Interleukin Related
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