Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 6-(3,4-dihydroxyphenyl)-4-hydroxy-3Z,5E-hexadien-2-one
Purity: ≥95%
Formula Markup: C12H12O4
Formula Weight: 220.0
CAS Number: 173933-40-9
Notes: Hispolon is a phenol originally isolated from I. hispidus that has diverse biological activities.{68710,68709,68711} It scavenges superoxide and hydroxyl radicals in cell-free assays, as well as reduces LPS-induced production of reactive oxygen species (ROS) in RAW 264.7 cells when used at concentrations of 5 and 10 µM.{68709} Hispolon (60-80 µM) inhibits cell proliferation and induces apoptosis in C6 rat glioma and DBTRG-05MG human glioblastoma cells.{68710} Hispolon (5 and 10 mg/kg) reduces tumor volume in a DBTRG-05MG mouse xenograft model. It also reduces acetic acid-induced writhing in mice when administered at a dose of 20 mg/kg.{68711}
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