Clone Name: HNF1B/9518
Light Chain: Kappa
Application Note: IHC-P: 1-2μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Positive Control: Human kidney, pancreas or liver tissue
Form: Liquid
Buffer (with preservative): PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% Sodium Azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Uniprot ID: P35680
Antigen Species: Human
Immunogen: Recombinant fragment (1-200 aa) of human HNF1B protein
Purification: Purified by Protein A/G
Conjugation: Unconjugated
Full Name: HNF1 homeobox B
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