Product Description: HPK1-IN-4 (comp 22) is a HPK1 (MAPK41) inhibitor (IC50 of 0.061 nM) as preclinical immunoresearch tool compound[1].
Applications: Cancer-Kinase/protease
Formula: C23H26N6O3
References: [1]Brandon A Vara, et al. Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds. ACS Med Chem Lett. 2021 Mar 19;12(4):653-661.
CAS Number: 2739844-28-9
Molecular Weight: 434.49
Compound Purity: 99.42
Research Area: Cancer
Solubility: DMSO : 100 mg/mL (ultrasonic;adjust pH to 4 with HCl)